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Hylaform/Hylaform Plus Dermal Fillers

Manufactured by Inamed Aesthetics, and approved by the Food and Drug Administration in 2004, Hylaform/Hylaform Plus is a hyaluronic acid based dermal filler, used for moderate to severe lines and wrinkles produced by aging, and collagen degradation. It is also used in medicine, to treat, and help to manage osteoarthritis. It is a clear, injectable gel produced from specially bred rooster combs, and tends to last longer than other dermal fillers.

The Hylaform Difference

The hyaluronic acid used in Hylaform/Hylaform Plus, is harvested from the connective tissues in the fleshy portion of the top of the rooster’s head, called rooster comb. The roosters are specially bred for the purpose of making Hylaform products, and the rooster tissue is then purified, sterilized, and then stabilized chemically, into a clear gel form. It is minimally modified, so no skin test is required, but you should not use Hylaform if you are allergic to eggs or feathers.

Hypersensitivity is rare, but it could occur to individuals with bird allergies, however, there is absolutely no risk of contracting bird flu from Hylaform. When Hylaform is modified with the rooster comb hyaluronic acid, it is purified, then sterilized at a temperature which is higher than necessary to kill the bird flu virus. Both Hylaform, and Hylaform Plus last longer than bovine (cow) dermal fillers, and do not require pre-testing, for skin allergies.

The Difference Between Hylaform And Hylaform Plus

Both types of Hylaform integrate into the dermis, and bind with water molecules, adding volume to and rehydrating skin. Hylaform has intermediate sized gel particles, similar to Restylane and Captique, and is suitable for moderate, facial wrinkle injections, and lip enhancement. Both are injected into the dermal layer of skin, however, Hylaform is injected nearer the beginning of the dermal layer.

Hylaform Plus consists of larger gel particles, such as Perlane, and is used for deeper lines, facial contouring, and lip enhancement. It is injected deeper into the dermal layer of skin, to add volume to, and to fill the more severe facial wrinkles. Because Hylaform Plus is injected deeper into the dermal layer, and the gel particle size is larger, it lasts longer than Hylaform.


Immediate Treatment
There is no pre-testing on the skin for allergies required. If you are allergic to eggs or feathers however, you should not use this product.

Immediate Results
There is no waiting for weeks, to months for results. After just a few days, the results can be seen.

Approved By FDA
This product has been used internationally for almost 10 years, and was approved by the Food and Drug Administration in 2004, for use in the United States.

Mild Side Effects
There is less bruising, swelling, and redness usually experienced than with other dermal facial injections.

Hylaform/Hylaform Plus injections, on the average, last longer than its collagen filler counterparts. Hylaform usually lasts approximately 6-12 months.

Less Risk Of Nodules Forming
Because Hylaform is a gel, there is less of a risk of nodules forming around injection area. Small bumps may however, be felt before the injections blend into the skin’s dermal layer.

Treatments Cost Less
Hylaform usually costs less than other dermal filler treatments such as Captique, or Restylane, mainly because you will need fewer injections. The cost per injection is almost the same, at $650, yet you may have to receive fewer treatments, depending on areas and severity of treatment.

Risks Of Hylaform/Hylaform Plus

Hylaform/Hylaform Plus does not contain lidocaine (anesthetic) in the injectable gel, and the injections may be more uncomfortable than those containing an anesthetic.

Hylaform may exhibit a higher rate of adverse reaction, compared to other Hyaluronic acid fillers such as Restylane and Captique.

Hylaform precautions are similar to all hyaluronic acid facial injections. You must be over 18, and not pregnant, or breast feeding. You will also need to possibly stop taking medications containing blood thinners, and you must not have an autoimmune disease.

The Injection Procedure

The dermal filler injection treatments follow the same procedures, with only subtle variance with different products. After consulting with your chosen doctor, and results are discussed, the injection spots will be scored or drawn on your skin, the skin will be cleaned and treated with a local anesthetic, and injections will only take seconds. The entire course of treatment mainly consists of discussing your medical history, and desired results with your doctor. therefore treatments may take 15-30 minutes.

You may experience redness and swelling for at least a few hours or days, and you may experience moderate stinging and burning during injections, because there is no lidocaine in the injection. There is really no down time, other than this. If you have had lip injections, there is a risk of lip asymmetry and swelling for the first 1-2 weeks, before the injection blends into your own dermis.


Most reviewers who have had both types of injection, preferred Hylaform Plus, over Botox. Hylaform is not used as much as Hylaform Plus, because most people prefer the deeper, longer-lasting form of Hylaform. Hylaform Plus works the best on frown lines, and lasts longer than other treatments, on most patients. The injections may have been a little more uncomfortable than those with lidocaine, but the lasting results, made Hylaform Plus dermal filler “worth the pain” for most patients.

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